Membrane Filtration for Separation of Polysaccharides from Fermentation Broth of Ganoderma lucidum

Ultrafiltration was used for the separation of polysaccharides from the fermentation broth of Ganoderma lucidum to simulate industrial production.Meanwhile,the molecular weight distribution of the fermentation broth and its filtrate and retentate was investigated by AcA44 gel chromatography.Results showed that ultrafilitration resulted in the removal of parts of small molecule weight polysaccharides,the increase of proportion of big molecule weight ones and the obvious improvement of quality of products resulting from the following ethanol precipitation.