2006Chinese Journal of PharmaceuticalsRequires access

Determination of in vitro Adhesive Force and Its Application in Formulation of Bioadhesive Tablets

Zhao Gao

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Abstract

The adhesive ability of the prepared bioadhesive tablets was measured using excised small intestine of same rat by domestic adhesive force determination device. The formulation was optimized using adhesive force and in vitro release as two evaluation parameters. The results showed that domestic device was simple and the method could be used to screen the formulation of bioadhesive preparations.

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What this paper is about

The adhesive ability of the prepared bioadhesive tablets was measured using excised small intestine of same rat by domestic adhesive force determination device. The formulation was optimized using adhesive force and in vitro release as two evaluation parameters. The results showed that domestic device was simple and the method could be used to screen the formulation of bioadhesive preparations.

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Available abstract

The adhesive ability of the prepared bioadhesive tablets was measured using excised small intestine of same rat by domestic adhesive force determination device. The formulation was optimized using adhesive force and in vitro release as two evaluation parameters. The results showed that domestic device was simple and the method could be used to screen the formulation of bioadhesive preparations.

Key concepts: Bioadhesive, Adhesive, Chemistry, In vitro, Chromatography, Biomedical engineering, Nanotechnology, Polymer

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