Clinical Observation on the Treatment of Cervical Chlamydia Trachomatis Infection Using Four Antibiotics

Objective:To compare the clinical effects of four antibiotics in the treatment of cervical chlamydia trachomatis infection. Methods:258 patients with genital tract chlamydia trachomatis infections were divided into 4 groups according to their registration numbers which were the moxifloxacin group (n =63),the clarithromycin group (n =63),the azithromycin group (n =65) and the minocycline group (n =67). Chlamydia trachomatis detections by cervical swabs were performed at the 21th and 60th day after the end of medication. And clinical effects were evaluated according to the results of laboratory examinations. Results:The negative-turning rates of microbiology in the 4 groups were 88.89% ,71.43% ,75.38% and 86.57% ,respectively. Statistical significance was showed in the differences of negative-turning rates between the moxifloxacin group and the clarithromycin as well as azithromycin group (P0.05). Recurrence rates at the 60th day were respectively 3.7%,8.9%,4.1% and 3.5%,with no significant differences among the 4 groups. Conclusions:These 4 antibiotics are all effective on chlamydia trachomatis infections. Moxifloxacin and minocycline are relatively superior for the treatment of genital tract chlamydia trachomatis infections. The results of our experiment will provide some evidences for clinical drug choices.