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2014•Xiandai shengwu yixue jinzhanRequires access

Effect of bFGF on the Biological Properties of Cartilage

Siji Li

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Abstract

Basic fibroblast growth factor(bFGF) is an important promoting factor in mitosis. bFGF can be passed as the mesoderm and neural signal to promote the development of Ectodermal Dysplasia cell division, and cell morphogenesis and differentiation-inducing factor, growth and organizations involved in cartilage injury and repair process. Especially bFGF play an important role in proliferation and differentiation of chondrocytes which to provide reference value in solve the problem of tissue engineered cartilage and to cure osteoarthritis. This article makes a summary in effect of bFGF on the biological properties of cartilage, which is differentiation, proliferation, apoptosis.

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What this paper is about

Basic fibroblast growth factor(bFGF) is an important promoting factor in mitosis. bFGF can be passed as the mesoderm and neural signal to promote the development of Ectodermal Dysplasia cell division, and cell morphogenesis and differentiation-inducing factor, growth and organizations involved in cartilage injury and repair process. Especially bFGF play an important role in proliferation and differentiation of chondrocytes which to provide reference value in solve the problem of tissue engineered cartilage and to cure osteoarthritis. This article makes a summary in effect of bFGF on the biological properties of cartilage, which is differentiation, proliferation, apoptosis.

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Available abstract

Basic fibroblast growth factor(bFGF) is an important promoting factor in mitosis. bFGF can be passed as the mesoderm and neural signal to promote the development of Ectodermal Dysplasia cell division, and cell morphogenesis and differentiation-inducing factor, growth and organizations involved in cartilage injury and repair process. Especially bFGF play an important role in proliferation and differentiation of chondrocytes which to provide reference value in solve the problem of tissue engineered cartilage and to cure osteoarthritis. This article makes a summary in effect of bFGF on the biological properties of cartilage, which is differentiation, proliferation, apoptosis.

Key concepts: Basic fibroblast growth factor, Cartilage, Cell biology, Fibroblast growth factor, Growth factor, Mitosis, Morphogenesis, Cell growth

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