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Study on Detection Method of Serum Prostate Specific Antigen of Prostate Disease Patients

Jin Zhang

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Abstract

As one of the detection of tumor marker for prostate cancer,prostate specific antigen(PSA) has been paid more and more attention at home.This article briefly introduces the biological characteristics and the basic principle and the method characteristics of test methods of PSA including enzyme linked immunosorbent assay(ELISA),radioimmunoassay(RIA),chemical luminescence immunoassay(LICA) and Electrochemiluminescence immunoassay(ECLIA),and the significance of PSA in the diagnosis of prostate cancer is also reviewed.PSA is the most useful immunocytochemical marker,whose specificity and sensitivity to confirm whether a certain tissue is from prostate are as high as 100%.

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What this paper is about

As one of the detection of tumor marker for prostate cancer,prostate specific antigen(PSA) has been paid more and more attention at home.This article briefly introduces the biological characteristics and the basic principle and the method characteristics of test methods of PSA including enzyme linked immunosorbent assay(ELISA),radioimmunoassay(RIA),chemical luminescence immunoassay(LICA) and Electrochemiluminescence immunoassay(ECLIA),and the significance of PSA in the diagnosis of prostate cancer is also reviewed.PSA is the most useful immunocytochemical marker,whose specificity and sensitivity to confirm whether a certain tissue is from prostate are as high as 100%.

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Available abstract

As one of the detection of tumor marker for prostate cancer,prostate specific antigen(PSA) has been paid more and more attention at home.This article briefly introduces the biological characteristics and the basic principle and the method characteristics of test methods of PSA including enzyme linked immunosorbent assay(ELISA),radioimmunoassay(RIA),chemical luminescence immunoassay(LICA) and Electrochemiluminescence immunoassay(ECLIA),and the significance of PSA in the diagnosis of prostate cancer is also reviewed.PSA is the most useful immunocytochemical marker,whose specificity and sensitivity to confirm whether a certain tissue is from prostate are as high as 100%.

Key concepts: Immunoassay, Prostate-specific antigen, Radioimmunoassay, Prostate cancer, PCA3, Prostatic disease, Prostate, Medicine

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