Phosphorus magnetic resonance spectroscopy at 3.0 Telsa in malignant fibrous histiocytoma and metastatic tumor

Objective To investigate the phosphorus magnetic resonance spectroscopy at 3.0 Telsa imaging features of malignant fibrous histiocytoma and metastatic tumors and to analyze the corresponding 31P magnetic resonance spectroscopy features.Methods Phosphorus magnetic resonance spectroscopy at 3.0 Telsa and single voxel phosphorus spectrum examination were performed in 10 healthy adults,6 cases of malignant fibrous histiocytoma and 8 cases of metastases to analyze the imaging features and metabolites characteristics.Results The phosphocreatine area,total adenosine triphosphate,peak height of phosphocreatine and ratio of phosphocreatine to inorganic phosphorus decreased,and the peak height of phosphomonoesterase,pH,ratio of phosphomonoesterase to nucleoside triphosphate and ratio of β-adenosine triphosphate to inorganic phosphorus increased in malignant fibrous histiocytoma compared with control group.The phosphocreatine area,peak height of phosphocreatine,ratio of phosphocreatine to inorganic phosphorus,ratio of phosphocreatine to nucleoside triphosphate and ratio of phosphocreatine to β-adenosine triphosphate decreased,and pH,ratio of phosphomonoesterase to nucleoside triphosphate and ratio of phosphodiester to nucleoside triphosphate increased in metastases group compared with control group(P0.05).There were no significant differences in the metabolites and relevant ratios between the malignant fibrous histiocytoma group and metastases group(P0.05).Conclusion Phosphorus magnetic resonance spectroscopy at 3.0 Telsa can clearly demonstrate malignant fibrous histiocytoma and metastatic tumor,and phosphorus spectroscopy can help to analyze the biochemical information of tumors.