Observing the Effect of Acupuncture on Metabolism of Study Memorizing Ability and the Quantity of AchE System in Brain of AD Rats
Wei Zhao
Abstract
Wei Zhao
Abstract
Objective:To observe the effect of acupuncture on the study of memori-zing ability and the quantity of AchE system in brain of AD rats of neural stem cell transplantation of hippocampus and discuss the mechanism of acupuncture cure the AD.Methods:The model was made by injecting β-AP to CA1 of hippocampus,the rats were randomly divided into normal group,model group,transplantal group,acupunctural group and transplantal acupuncture group,each group has 12 cases.Baihui,dazhui and renzhong point were selected for the acupuncture group which were connected by the electronic needle device.The memorizing ability was measured by using the diving tower of rats and enzyme-immunossay methods in cerebral cortex,the content of hippocamous ChAT was examined by ELISA method.Results:The reaction period of step down and the times of memory in transplantal acupuncture decrease(P0.05) than the model group,and the quantity of ChAT in cerebral cortex and hippocampus of the transplantal acupuncture group increase(P0.05) than the model group.There are obvious differences between the transplantal acupuncture group and the transplantal group(P0.05).Conclusion:The quantity of AchE system in brain of AD rats can be improved by acupuncture and acupuncture combined with transplant of Neural stem cell has better treatment effect.
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Objective:To observe the effect of acupuncture on the study of memori-zing ability and the quantity of AchE system in brain of AD rats of neural stem cell transplantation of hippocampus and discuss the mechanism of acupuncture cure the AD.Methods:The model was made by injecting β-AP to CA1 of hippocampus,the rats were randomly divided into normal group,model group,transplantal group,acupunctural group and transplantal acupuncture group,each group has 12 cases.Baihui,dazhui and renzhong point were selected for the acupuncture group which were connected by the electronic needle device.The memorizing ability was measured by using the diving tower of rats and enzyme-immunossay methods in cerebral cortex,the content of hippocamous ChAT was examined by ELISA method.Results:The reaction period of step down and the times of memory in transplantal acupuncture decrease(P0.05) than the model group,and the quantity of ChAT in cerebral cortex and hippocampus of the transplantal acupuncture group increase(P0.05) than the model group.There are obvious differences between the transplantal acupuncture group and the transplantal group(P0.05).Conclusion:The quantity of AchE system in brain of AD rats can be improved by acupuncture and acupuncture combined with transplant of Neural stem cell has better treatment effect.
Key concepts: Acupuncture, Hippocampus, Medicine, Memorization, Aché, Anesthesia, Cortex (anatomy), Internal medicine