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CT and PET-CT manifestations and pathological features of solitary fibrous tumor

HU Sheng-pin

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Abstract

Objective:To explore CT and FDG-PET/CT imaging findings and pathological features of solitary fibrous tumor(SFT).Methods:The CT and FDG-PET/CT imaging features of nine patients with pathologically proved SFT were analyzed retrospectively.All patients underwent unenhanced and enhanced CT scan,of which 4cases also underwent PETCT examination.Results:Of 9cases,location of the SFTs was chest(n=5),including one case with multiple lesions,abdomen(n=2)and paraspinal(n=2).Tumor size was 0.9~12.3cm,mean(4.2±2.0)cm.On pre-contrast enhanced CT images,homogeneous low to moderate density was showed in 7cases,and inhomogeneous densitsy with small areas of lower density was showed in 2cases.On arterial phase images of contrast enhanced CT,unevenly moderate to intensive enhancement was demonstrated in 6cases,and mild enhancement in 3cases;in the venous phase,continuous enhancement with or without irregular non-enhanced areas was showed in all cases.The SPFs of 5cases were attached to costal or mediastinal pleura and peritoneum with wide base,the SPFs of 2cases were attached to mensentery.PET-CT showed high FDG uptake was exsited in 4SFTs,the mean maximal standard uptake value(SUVmax)of the lesions was 6.7±7.0(range from 2.7to19.2).Conclusion:SFT has some characteristic manifestations on CT,with increased FDG uptake on PET-CT,but the SUVmax is not a valuable parameter for the diagnosis of malignant SFT.

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Objective:To explore CT and FDG-PET/CT imaging findings and pathological features of solitary fibrous tumor(SFT).Methods:The CT and FDG-PET/CT imaging features of nine patients with pathologically proved SFT were analyzed retrospectively.All patients underwent unenhanced and enhanced CT scan,of which 4cases also underwent PETCT examination.Results:Of 9cases,location of the SFTs was chest(n=5),including one case with multiple lesions,abdomen(n=2)and paraspinal(n=2).Tumor size was 0.9~12.3cm,mean(4.2±2.0)cm.On pre-contrast enhanced CT images,homogeneous low to moderate density was showed in 7cases,and inhomogeneous densitsy with small areas of lower density was showed in 2cases.On arterial phase images of contrast enhanced CT,unevenly moderate to intensive enhancement was demonstrated in 6cases,and mild enhancement in 3cases;in the venous phase,continuous enhancement with or without irregular non-enhanced areas was showed in all cases.The SPFs of 5cases were attached to costal or mediastinal pleura and peritoneum with wide base,the SPFs of 2cases were attached to mensentery.PET-CT showed high FDG uptake was exsited in 4SFTs,the mean maximal standard uptake value(SUVmax)of the lesions was 6.7±7.0(range from 2.7to19.2).Conclusion:SFT has some characteristic manifestations on CT,with increased FDG uptake on PET-CT,but the SUVmax is not a valuable parameter for the diagnosis of malignant SFT.

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Available abstract

Objective:To explore CT and FDG-PET/CT imaging findings and pathological features of solitary fibrous tumor(SFT).Methods:The CT and FDG-PET/CT imaging features of nine patients with pathologically proved SFT were analyzed retrospectively.All patients underwent unenhanced and enhanced CT scan,of which 4cases also underwent PETCT examination.Results:Of 9cases,location of the SFTs was chest(n=5),including one case with multiple lesions,abdomen(n=2)and paraspinal(n=2).Tumor size was 0.9~12.3cm,mean(4.2±2.0)cm.On pre-contrast enhanced CT images,homogeneous low to moderate density was showed in 7cases,and inhomogeneous densitsy with small areas of lower density was showed in 2cases.On arterial phase images of contrast enhanced CT,unevenly moderate to intensive enhancement was demonstrated in 6cases,and mild enhancement in 3cases;in the venous phase,continuous enhancement with or without irregular non-enhanced areas was showed in all cases.The SPFs of 5cases were attached to costal or mediastinal pleura and peritoneum with wide base,the SPFs of 2cases were attached to mensentery.PET-CT showed high FDG uptake was exsited in 4SFTs,the mean maximal standard uptake value(SUVmax)of the lesions was 6.7±7.0(range from 2.7to19.2).Conclusion:SFT has some characteristic manifestations on CT,with increased FDG uptake on PET-CT,but the SUVmax is not a valuable parameter for the diagnosis of malignant SFT.

Key concepts: Medicine, Solitary fibrous tumor, Radiology, Nuclear medicine, Abdomen, Pathological, Homogeneous, Computed tomography

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