ScholarLens Back to search
2007•Zhongguo fuyou baojianRequires access

Clinical and genetic analysis on the influence of Y chromosome abnormality on male reproductive ability

Gao Jiu

Open publisher page 0 citations

Abstract

Objective:To investigate the influence of Y chromosome abnormality on male reproductive ability.Methods:1 656 consultative patients were performed by peripheral blood lymphocytes culturing to make chromosome G-banding and analyze the karyotype by standard techniques.Results:30 cases of Y chromosome abnormality were observed in 1 656 patients,abnormal chromosome rate was 1.81%(30/1 656).Among the 30 cases,5 cases of numeric aberrations were found,accounting for 16.67%;25 cases of structural aberrations were found,accounting for 83.33%,including 4 cases of 45,XO mosaic 46,XY;1 cases of Robertsonian translocation 45,X,-Y,-13,+t(Y;13)(p1;q10);11 cases of big Y chromosome abnormality;14 cases of small Y chromosome abnormality.Conclusion:Chromosome abnormality is an important factor resulting in male reproductive ability.

About this research paper

What this paper is about

Objective:To investigate the influence of Y chromosome abnormality on male reproductive ability.Methods:1 656 consultative patients were performed by peripheral blood lymphocytes culturing to make chromosome G-banding and analyze the karyotype by standard techniques.Results:30 cases of Y chromosome abnormality were observed in 1 656 patients,abnormal chromosome rate was 1.81%(30/1 656).Among the 30 cases,5 cases of numeric aberrations were found,accounting for 16.67%;25 cases of structural aberrations were found,accounting for 83.33%,including 4 cases of 45,XO mosaic 46,XY;1 cases of Robertsonian translocation 45,X,-Y,-13,+t(Y;13)(p1;q10);11 cases of big Y chromosome abnormality;14 cases of small Y chromosome abnormality.Conclusion:Chromosome abnormality is an important factor resulting in male reproductive ability.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective:To investigate the influence of Y chromosome abnormality on male reproductive ability.Methods:1 656 consultative patients were performed by peripheral blood lymphocytes culturing to make chromosome G-banding and analyze the karyotype by standard techniques.Results:30 cases of Y chromosome abnormality were observed in 1 656 patients,abnormal chromosome rate was 1.81%(30/1 656).Among the 30 cases,5 cases of numeric aberrations were found,accounting for 16.67%;25 cases of structural aberrations were found,accounting for 83.33%,including 4 cases of 45,XO mosaic 46,XY;1 cases of Robertsonian translocation 45,X,-Y,-13,+t(Y;13)(p1;q10);11 cases of big Y chromosome abnormality;14 cases of small Y chromosome abnormality.Conclusion:Chromosome abnormality is an important factor resulting in male reproductive ability.

Key concepts: Abnormality, Chromosomal translocation, Karyotype, Chromosome, Chromosome abnormality, Chromosomal Abnormality, Robertsonian translocation, Peripheral blood

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Clinical and genetic analysis on the influence of Y chromosome abnormality on male reproductive ability — Research Paper | ScholarLens