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2009•Journal of Capital Medical UniversityRequires access

Progress in Studies on Mechanism of Hepatitis C Virus Resistance to Interferon Treatment

Xinyue Chen

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Abstract

Interferon plays a critical role in the host's natural defense against viral infections and in their treatment. Interferon is one of the two drugs that constitute the only antiviral therapy for hepatitis C virus(HCV) infection; however,in a certain proportion of cases the virus is resistant to interferon. Several HCV proteins have been shown to possess properties that enable the virus to evade the interferon-mediated cellular antiviral responses.

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What this paper is about

Interferon plays a critical role in the host's natural defense against viral infections and in their treatment. Interferon is one of the two drugs that constitute the only antiviral therapy for hepatitis C virus(HCV) infection; however,in a certain proportion of cases the virus is resistant to interferon. Several HCV proteins have been shown to possess properties that enable the virus to evade the interferon-mediated cellular antiviral responses.

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Available abstract

Interferon plays a critical role in the host's natural defense against viral infections and in their treatment. Interferon is one of the two drugs that constitute the only antiviral therapy for hepatitis C virus(HCV) infection; however,in a certain proportion of cases the virus is resistant to interferon. Several HCV proteins have been shown to possess properties that enable the virus to evade the interferon-mediated cellular antiviral responses.

Key concepts: Interferon, Virology, Hepatitis C virus, Virus, Immunology, Mechanism (biology), Biology, Medicine

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