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Studies on Chemical Constituents of Angelica dahurica

Feng Xu

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Abstract

Objective To study the chemical constituents of Angelica dahurica.Methods The constituents were isolated and purified by silica gel,RP-18,and Sephadex LH-20 column chromatography.Their structures were identified by physiochemical properties and spectral analysis.Results Five compounds were isolated and identified as 7-O-β-D-Apiofuranosyl-(1→6)-β-D-Glucopyranosyl-Scopoletin①,aesculetin-6-O-β-D-apiofuranosyl-(1→6)-O-β-D-glucopyranoside②,tomenin③,isoscopolin④,Osmanthuside H⑤.Conclusion Compound 1 to 5 were obtained from Umbeliferae for the first time.

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Objective To study the chemical constituents of Angelica dahurica.Methods The constituents were isolated and purified by silica gel,RP-18,and Sephadex LH-20 column chromatography.Their structures were identified by physiochemical properties and spectral analysis.Results Five compounds were isolated and identified as 7-O-β-D-Apiofuranosyl-(1→6)-β-D-Glucopyranosyl-Scopoletin①,aesculetin-6-O-β-D-apiofuranosyl-(1→6)-O-β-D-glucopyranoside②,tomenin③,isoscopolin④,Osmanthuside H⑤.Conclusion Compound 1 to 5 were obtained from Umbeliferae for the first time.

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Available abstract

Objective To study the chemical constituents of Angelica dahurica.Methods The constituents were isolated and purified by silica gel,RP-18,and Sephadex LH-20 column chromatography.Their structures were identified by physiochemical properties and spectral analysis.Results Five compounds were isolated and identified as 7-O-β-D-Apiofuranosyl-(1→6)-β-D-Glucopyranosyl-Scopoletin①,aesculetin-6-O-β-D-apiofuranosyl-(1→6)-O-β-D-glucopyranoside②,tomenin③,isoscopolin④,Osmanthuside H⑤.Conclusion Compound 1 to 5 were obtained from Umbeliferae for the first time.

Key concepts: Scopoletin, Sephadex, Chemical constituents, Chromatography, Chemistry, Silica gel, Column chromatography, Traditional medicine

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