Effect of Whole Body Subthermia on the Content of Cell Apoptosis of the Brain Tiussue Following Hypoxia-ischemia Brain Damage in Neonotol Rats
Jun Zhang
Abstract
Jun Zhang
Abstract
Research on the effect of subthermia on cell apoptosis of the brain of neonatal rats with hypoxia ischemic brain damage is reviewed.33℃subthermis intervenes in the model for six hours immediately after rats model was established by inhauling the mixed gases of 8% O 2 and 92% N 2.The number of apoptosis cell is tested by Terminal Deoxy Transferase Uridine Triphosphate Nick End Labeling(TUNEL).The results indicate that subthermia can significantly reduce the number of apoptosis cell,playing a protective role in hypoxia ischemic brain damage.
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Research on the effect of subthermia on cell apoptosis of the brain of neonatal rats with hypoxia ischemic brain damage is reviewed.33℃subthermis intervenes in the model for six hours immediately after rats model was established by inhauling the mixed gases of 8% O 2 and 92% N 2.The number of apoptosis cell is tested by Terminal Deoxy Transferase Uridine Triphosphate Nick End Labeling(TUNEL).The results indicate that subthermia can significantly reduce the number of apoptosis cell,playing a protective role in hypoxia ischemic brain damage.
Key concepts: TUNEL assay, Apoptosis, Hypoxia (environmental), Brain Cell, Brain damage, Uridine, Cell, Ischemia