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2003•Zhongguo yaowu yilaixing zazhiRequires access

NALTREXONE THERAPY FOR HEROIN ADDICTS

JI Hanbing

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Abstract

Objective: To investigate the effect of naltrexone on the prevention of drug relapse. Methods: Retrospective study was conducted. The clinical data of 50 drug addicts who administered naltrexone to prevent relapse after detoxification were analyzed. Results: After six-month administration of naltrexone, the scores of craving for heroin decreased from 1.96±s 0.88 to 0.25±s 0.44; the relapse rate decreased from 28.6% to 5.0%; of 17 former intravenous injecting drug users, when they relapsed, 11 changed to snorting and one changed to in.Conclusion: Naltrexone can alleviate or even eliminate the positive enforcement of heroin so that it can reduce the addicts' craving for heroin and the rate of their relapse. The adverse reaction is slight.

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What this paper is about

Objective: To investigate the effect of naltrexone on the prevention of drug relapse. Methods: Retrospective study was conducted. The clinical data of 50 drug addicts who administered naltrexone to prevent relapse after detoxification were analyzed. Results: After six-month administration of naltrexone, the scores of craving for heroin decreased from 1.96±s 0.88 to 0.25±s 0.44; the relapse rate decreased from 28.6% to 5.0%; of 17 former intravenous injecting drug users, when they relapsed, 11 changed to snorting and one changed to in.Conclusion: Naltrexone can alleviate or even eliminate the positive enforcement of heroin so that it can reduce the addicts' craving for heroin and the rate of their relapse. The adverse reaction is slight.

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Available abstract

Objective: To investigate the effect of naltrexone on the prevention of drug relapse. Methods: Retrospective study was conducted. The clinical data of 50 drug addicts who administered naltrexone to prevent relapse after detoxification were analyzed. Results: After six-month administration of naltrexone, the scores of craving for heroin decreased from 1.96±s 0.88 to 0.25±s 0.44; the relapse rate decreased from 28.6% to 5.0%; of 17 former intravenous injecting drug users, when they relapsed, 11 changed to snorting and one changed to in.Conclusion: Naltrexone can alleviate or even eliminate the positive enforcement of heroin so that it can reduce the addicts' craving for heroin and the rate of their relapse. The adverse reaction is slight.

Key concepts: Naltrexone, Craving, Heroin, Detoxification (alternative medicine), Addiction, Heroin dependence, Medicine, Adverse effect

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