Analysis of Hepatitis B Virus Infection among Natural Population in Fuzhou City From 2005 to 2006

[Objective]The present study was conducted to find out the current situation of viral hepatitis B(HBV) infection and provide scientific basis to improve hepatitis B prevention in Fuzhou.[Methods]Investigate on HBV infection was conducted among the natural population randomly selected from December,2005 to March,2006.[Results]1 538 people were investigated.The infection rate of HBV was 59.56%.Of them the positive rate of HBsAg,anti-HBs,HBeAg,anti-HBe,anti-HBc was 13.33%,53.25%,2.28%,17.04% and 56.83% respectively.Of all the targets both anti-HBs and antiHBc were positive accounted for 25.75%.Geographically,The prevalence rate of HBsAg,HBeAg in coastal were higher than that in the plains and mountains(P0.05);the prevalence rate of HBsAg and anti-HBs was higher in the people aged from 15 to 49 year olds(P0.01);the prevalence rate of HBsAg shows Family Aggregation.The positive rate of HBsAg,anti-HBs and anti-HBc was lower in immunized people than that in un-immunized people(P0.01).[Conclusion]The results showed that the positive rate of HBV in Fuzhou is higher than the national average level.Immunization with hepatitis B vaccine should be strengthened in coastal areas and the HBV infection persons' family members.