Effect of pre- pregnancy body mass index and gestational weight on maternal and infantile outcomes

Objective: To explore the effect of pre- pregnancy body mass index( BMI) and gestational weight on maternal and infantile outcomes. Methods: The clinical data of 688 pregnant women were retrospectively analyzed,including pre- pregnancy BMI,body weight gain during pregnancy,maternal and infantile outcomes. Results: There were statistically significant differences in the incidence rates of hypertensive disorder complicating pregnancy( HDCP),neonatal birth weight and neonatal asphyxia among the pregnant women with different pre- pregnancy BMI( P 0. 05); there were statistically significant differences in fetal age,the incidence rates of HDCP and gestational diabetes mellitus( GDM) and neonatal birth weight among the pregnant women with different body weight gains during pregnancy( P 0. 05). The results of Logistic regression analysis showed that low pre- pregnancy BMI was the risk factor of low birth weight infants( P 0. 05),high pre- pregnancy BMI was the risk factor of HDCP,macrosomia and neonatal asphyxia( P 0. 05); low body weight gain during pregnancy was the risk factor of premature birth,GDM and low birth weight infants( P 0. 05),excessive body weight gain during pregnancy was the risk factor of HDCP,GDM and macrosomia( P 0. 05). Conclusion: Low or high pre- pregnancy BMI and inappropriate body weight gain during pregnancy are correlated with adverse maternal and infantile outcomes,BMI of women of childbearing age should be adjusted to appropriate range,the pregnant women should pay more attention to reasonable nutritional supplementation,perinatal management and clinical intervention should be strengthened among the pregnant women with abnormal body weight gain during pregnancy to reduce the risk of adverse perinatal outcome.