The Relationship Between Helicobacter Pylori Infection and Gastric Polyps

Objective To investigate the relationship between Helicobacter pylori(H. pylori) infection and gastric polyps in dif-ferent types. Methods 106 cases of gastric polyps were diagnosed by gastroscope and histopathothologic examination, the polypsobtained by gastroscope were HE stained to determine the histological types and the level of inflammatory response. At the same, 2or 3 gastric mucosa biopsy specimen were taken from gastric antrum and rapid urea enzyme test and methylene blue staining wasmade to detect H. pylori infection: if both tests showed positive, the infection would be conformed by H. pylori. Results Out of the106 cases with gastric polyps, HP infection took up 65.1% 76 cases(71.7%) were hyperplastic polyps, 30 cases(28.3%) wereadenomaous polyps. THe H. pylori infection rate in hyperplastic polyps (56/76; 73.7%) was significantly higher than adenomaouspolyps(13/30; 43.1%) (P0.01). Active inflammatory response(42/76; 55.3%) was significantly ghigher in hyperplastic polypthan in adenomaous polyp(9/30; 30%) (P0.05). Conclusion The development of hyperplastic polyps is associated with H.pylori infection, which may be related to the active inflammatory response caused by H. pylori.