2014Lishizhen Medicine and Materia Medica ResearchRequires access

Studies on degradation kinetics of Hesperidin in aqueous

Wang Men

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Abstract

Objective To investigate the degradation kinetic characteristics of hesperidin in aqueous under different pH and temperatures. Methods The concentration change of hesperidin in aqueous solution was determined by HPLC under different pH and temperatures. Base on the chemical reaction kinetic,the parameters of degradation kinetics were calculated under different conditions. The activation energy and half-life were evaluated. Results The results indicated that thermal degradation kinetic model of hesperidin in aqueous solution follows first-order degradation kinetic process. The half-life period( t0. 5) was 2.56 hours under pH10 in aqueous solution,and the energy of activation( Ea) was 24. 73 kJ·mol-1. Conclusion Hesperidin was more stable in acidic aqueous solution and low temperature condition. The degradation of hesperidin can be observed in strong alkali conditions.

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What this paper is about

Objective To investigate the degradation kinetic characteristics of hesperidin in aqueous under different pH and temperatures. Methods The concentration change of hesperidin in aqueous solution was determined by HPLC under different pH and temperatures. Base on the chemical reaction kinetic,the parameters of degradation kinetics were calculated under different conditions. The activation energy and half-life were evaluated. Results The results indicated that thermal degradation kinetic model of hesperidin in aqueous solution follows first-order degradation kinetic process. The half-life period( t0. 5) was 2.56 hours under pH10 in aqueous solution,and the energy of activation( Ea) was 24. 73 kJ·mol-1. Conclusion Hesperidin was more stable in acidic aqueous solution and low temperature condition. The degradation of hesperidin can be observed in strong alkali conditions.

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Available abstract

Objective To investigate the degradation kinetic characteristics of hesperidin in aqueous under different pH and temperatures. Methods The concentration change of hesperidin in aqueous solution was determined by HPLC under different pH and temperatures. Base on the chemical reaction kinetic,the parameters of degradation kinetics were calculated under different conditions. The activation energy and half-life were evaluated. Results The results indicated that thermal degradation kinetic model of hesperidin in aqueous solution follows first-order degradation kinetic process. The half-life period( t0. 5) was 2.56 hours under pH10 in aqueous solution,and the energy of activation( Ea) was 24. 73 kJ·mol-1. Conclusion Hesperidin was more stable in acidic aqueous solution and low temperature condition. The degradation of hesperidin can be observed in strong alkali conditions.

Key concepts: Hesperidin, Aqueous solution, Chemistry, Kinetics, Degradation (telecommunications), Activation energy, Kinetic energy, Chromatography

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