Study on Apotosis of 293 Cells Induced by Cadmium Chloride
Zheng Li-shu
Abstract
Zheng Li-shu
Abstract
ve To explain apoptosis induced by cadmium chloride in 293 cells in vitro. Methods 293 cells were exposed to 0,12.5,25.0,50.0μmol/L of CdCl2 for various time period, to measure the apoptosis by DNA agarose electrophore-sis and ELISA. Results CdCl2 could induce apotosis of 293 cells in vitro at concentration of 12.50,25. 00, 50. 00μmol/L. Different concentration of CdCl2 could also cause reduction of cells survial associated with exposed doses and time and apoptosis. Conclusion Cadmium chloride coucld induce 293 cell apoptosis in vitro associated with exposed dose and time.
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ve To explain apoptosis induced by cadmium chloride in 293 cells in vitro. Methods 293 cells were exposed to 0,12.5,25.0,50.0μmol/L of CdCl2 for various time period, to measure the apoptosis by DNA agarose electrophore-sis and ELISA. Results CdCl2 could induce apotosis of 293 cells in vitro at concentration of 12.50,25. 00, 50. 00μmol/L. Different concentration of CdCl2 could also cause reduction of cells survial associated with exposed doses and time and apoptosis. Conclusion Cadmium chloride coucld induce 293 cell apoptosis in vitro associated with exposed dose and time.
Key concepts: Apoptosis, Cadmium chloride, In vitro, Chemistry, Cadmium, Chloride, Molecular biology, Agarose