2013•Shengwu jiagong guochengRequires access

Recent advances in bioreactor and its engineering

Siliang Zhang

Open publisher page 2 citations

Abstract

The engineering methodologies and key technologies for the bioreactor design and the scale-up were discussed.The development trends in bioreactors for the production of biotechnology products were described,including a bioreactor system focusing on metabolic flux detection and analysis,the improved stirred-tank bioreactor based on computational fluid dynamics,microbioreactor,bioreactor for mammalian cell,and enzymatic bioreactor.

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What this paper is about

The engineering methodologies and key technologies for the bioreactor design and the scale-up were discussed.The development trends in bioreactors for the production of biotechnology products were described,including a bioreactor system focusing on metabolic flux detection and analysis,the improved stirred-tank bioreactor based on computational fluid dynamics,microbioreactor,bioreactor for mammalian cell,and enzymatic bioreactor.

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Available abstract

The engineering methodologies and key technologies for the bioreactor design and the scale-up were discussed.The development trends in bioreactors for the production of biotechnology products were described,including a bioreactor system focusing on metabolic flux detection and analysis,the improved stirred-tank bioreactor based on computational fluid dynamics,microbioreactor,bioreactor for mammalian cell,and enzymatic bioreactor.

Key concepts: Bioreactor, Biochemical engineering, Flux (metallurgy), Metabolic engineering, SCALE-UP, Biotechnology, Chemistry, Biology

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