2005•Journal of Wenzhou Medical CollegeRequires access
Detection of extended-spectrum β-lactamase,AmpC enzyme and drug resistance in Acinetobacter baumannii
Zhongyong Wang
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Abstract
Objective: To detect the productive situation of extended-spectrum β-lactamase, AmpC enzyme in Acinetobacter baumannii. and investigate its character of drug resistance. Methods:ESBLs, AmpC enzyme were detected in 98 strains with three dimensional test respectively, antibiotic susceptibility test by VITEK-AMS and Kirby-Bauer test. Results: Among 98 strains of Acinetobacter baumannii, producing ESBLs bacteria accounted for 7 (7.1%); producing AmpC enzyme bacteria accounted for 17(17.3%). AmpC enzyme positive strains were multiplex resistant, and more resistant to antibiotics than AmpC enzyme negative strains. Conclusion: Producing AmpC enzyme was prominently cause of multiplex resistant in Acinetobacter baumannii. It should be decteded and treated carefully.