2008Shengming kexueRequires access

Progress on induced pluripotent stem cells

Fanyi Zeng

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Abstract

Recently,Cell、Science and Nature announced that several defined factors can induce human somatic cells into pluripotent stem cells that exhibit the essential characteristics of embryonic stem cells.And mouse iPS (induced pluripotent stem) cells have been used to treat humanized sickle cell anemia mouse model. The research on iPS cells by independent groups has acquired remarkable progress and attention,with the hot spots on reprogramming,dedifferentiation and the resource of pluripotent stem cells.

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What this paper is about

Recently,Cell、Science and Nature announced that several defined factors can induce human somatic cells into pluripotent stem cells that exhibit the essential characteristics of embryonic stem cells.And mouse iPS (induced pluripotent stem) cells have been used to treat humanized sickle cell anemia mouse model. The research on iPS cells by independent groups has acquired remarkable progress and attention,with the hot spots on reprogramming,dedifferentiation and the resource of pluripotent stem cells.

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Available abstract

Recently,Cell、Science and Nature announced that several defined factors can induce human somatic cells into pluripotent stem cells that exhibit the essential characteristics of embryonic stem cells.And mouse iPS (induced pluripotent stem) cells have been used to treat humanized sickle cell anemia mouse model. The research on iPS cells by independent groups has acquired remarkable progress and attention,with the hot spots on reprogramming,dedifferentiation and the resource of pluripotent stem cells.

Key concepts: Induced pluripotent stem cell, Reprogramming, Embryonic stem cell, Stem cell, Biology, Cell biology, Somatic cell, Induced stem cells

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