Clinical analysis of pregnancy outcomes of preterm premature rupture of membranes in 115 cases

Objective To analyze preterm premature rupture of membranes rupture of membranes and discuss the prognosis of the mother and neonates. Methods 115 cases of premature rupture of membranes in our hospital from December 2010 to December 2012 were retrospectively analyzed.And according to the gestational week,they were divided into three groups (28～31 +6 week for 25 cases,32～33 +6 week for 47 cases,34 week for 43 cases),the pregnancy outcome of three groups for analyzed. Results There were no significant differences of vaginal delivery rate and cesarean section rate between groups (P0.05);And there were significant differences of neonatal asphyxia,neonatal respiratory distress syndrome,neonatal pneumonia,intracranial hemorrhage,neonatal hypoxic ischemia encephalopathy,and perinatal death between the neonates of 28 to 31 +6 weeks and 34 weeks (P0.05).The perinatal death compared with 32 to 33 +6 weeks,the difference was statistically significant (P0.05); The neonatal asphyxia of 32 to 33 +6 weeks was sig- nificantly different from 34 weeks (P0.05). Conclusion Active treatment,anti-infection,promoting the maturity of fetal lung and extending gestational week can reduce the complications of preterm premature rupture of membranes and the neonatal mortality.