2009Chinese Journal of Clinical HepatologyRequires access

Analysis of 50 cases with HBV-Associated Glomerulonephritis

Liu Guo-yon

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Abstract

Objective To explore the clinical manifestation,check result and therapy of HBV-GN.Methods The clinical manifestation and check result were compared.The curative effects of alpha-interferon(IFNα)、ARB and ACEI for hepatitis B virus associated glomerulonephritis(HBV-GN) were observed.Results The common clinical situation were nephriticsyn-drome(NS) and microscopic hematuria,the ratio were 70% and 30% respectively;The constituent ratio of membranous nephropathy(MGN) and mesangiocapillary glomerulonephritis(MPGN) were 76% and 24% respectively;The ratio was 78% of normal liver function except albumin;The ratio was 92% of normal blood coagulation;The edema disappeared rate in the total number of patients with edema was 86% and the urine protein reduced was 83%.Conclusion Development of liver damage to patients with HBV-GN is slower than patients without HBV-GN;It may be useful that the treatment with antiviras and protecting kidney function for patients with HBV-GN.

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Objective To explore the clinical manifestation,check result and therapy of HBV-GN.Methods The clinical manifestation and check result were compared.The curative effects of alpha-interferon(IFNα)、ARB and ACEI for hepatitis B virus associated glomerulonephritis(HBV-GN) were observed.Results The common clinical situation were nephriticsyn-drome(NS) and microscopic hematuria,the ratio were 70% and 30% respectively;The constituent ratio of membranous nephropathy(MGN) and mesangiocapillary glomerulonephritis(MPGN) were 76% and 24% respectively;The ratio was 78% of normal liver function except albumin;The ratio was 92% of normal blood coagulation;The edema disappeared rate in the total number of patients with edema was 86% and the urine protein reduced was 83%.Conclusion Development of liver damage to patients with HBV-GN is slower than patients without HBV-GN;It may be useful that the treatment with antiviras and protecting kidney function for patients with HBV-GN.

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Available abstract

Objective To explore the clinical manifestation,check result and therapy of HBV-GN.Methods The clinical manifestation and check result were compared.The curative effects of alpha-interferon(IFNα)、ARB and ACEI for hepatitis B virus associated glomerulonephritis(HBV-GN) were observed.Results The common clinical situation were nephriticsyn-drome(NS) and microscopic hematuria,the ratio were 70% and 30% respectively;The constituent ratio of membranous nephropathy(MGN) and mesangiocapillary glomerulonephritis(MPGN) were 76% and 24% respectively;The ratio was 78% of normal liver function except albumin;The ratio was 92% of normal blood coagulation;The edema disappeared rate in the total number of patients with edema was 86% and the urine protein reduced was 83%.Conclusion Development of liver damage to patients with HBV-GN is slower than patients without HBV-GN;It may be useful that the treatment with antiviras and protecting kidney function for patients with HBV-GN.

Key concepts: Medicine, Glomerulonephritis, Gastroenterology, Renal function, Internal medicine, Hepatitis B virus, Edema, Hepatitis B

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