2013Tianran chanwu yanjiu yu kaifaRequires access

Studies on the Chemical Constituents from Sambucus adnata Wall

Wenshu Wang

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Abstract

Nine compounds were isolated from the methanol extract of the whole plants Sambucus adnata Wall.,which is a traditional medicine used by Dai people in south west of China.By analyzing spectroscopic data,especially NMR data,their structures were elucidated as 5 pentacyclic triterpenoids,including ursolic acid(1),oleanolic acid(2),α-amyrin(3),13β-hydroxy-11-en-ursolicacid(4),28-hydroxy-α-amyrin(5),2α,23-dihydroxyursolicacid(6),2α,3α,23-trihydroxyursolicacid(7),and a lignan 4-O-metbylcedrusin(8)and a steroid glycoside,β-daucosterol(9).Additionally,compounds 4-9 were isolated from Sambucus adnata Wall for the first time.

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What this paper is about

Nine compounds were isolated from the methanol extract of the whole plants Sambucus adnata Wall.,which is a traditional medicine used by Dai people in south west of China.By analyzing spectroscopic data,especially NMR data,their structures were elucidated as 5 pentacyclic triterpenoids,including ursolic acid(1),oleanolic acid(2),α-amyrin(3),13β-hydroxy-11-en-ursolicacid(4),28-hydroxy-α-amyrin(5),2α,23-dihydroxyursolicacid(6),2α,3α,23-trihydroxyursolicacid(7),and a lignan 4-O-metbylcedrusin(8)and a steroid glycoside,β-daucosterol(9).Additionally,compounds 4-9 were isolated from Sambucus adnata Wall for the first time.

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Available abstract

Nine compounds were isolated from the methanol extract of the whole plants Sambucus adnata Wall.,which is a traditional medicine used by Dai people in south west of China.By analyzing spectroscopic data,especially NMR data,their structures were elucidated as 5 pentacyclic triterpenoids,including ursolic acid(1),oleanolic acid(2),α-amyrin(3),13β-hydroxy-11-en-ursolicacid(4),28-hydroxy-α-amyrin(5),2α,23-dihydroxyursolicacid(6),2α,3α,23-trihydroxyursolicacid(7),and a lignan 4-O-metbylcedrusin(8)and a steroid glycoside,β-daucosterol(9).Additionally,compounds 4-9 were isolated from Sambucus adnata Wall for the first time.

Key concepts: Lignan, Ursolic acid, Oleanolic acid, Caprifoliaceae, Daucosterol, Chemistry, Traditional medicine, Chemical constituents

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