2005•Study Journal of Traditional Chinese MedicineRequires access

Effects of Huangjignzanyu Optimized Formula on Sperm Motility in Rat with Asthenospermia

Bao Liu, Wang Zuo, Zhao Houzuo, Bin Chen, Xia Zhongyuan

Abstract

Objective :To study the effects of Huangjingzanyu optimized formula on sperm motility in rat with asthenospermia. Methods :Rats with asthenospermia were induced by Multiglycosides of Tripterygium Wilfordii(GTW).Sperm motility velocity and motility mode were measured with computer-aidd sperm analysis(CASA). Results :Sperm concentration,motility,viability and motility velocity(VCL、VSL、VAP)were significantly increased in middle dosage of optimized formula.The effects of middle dosage group were similar to those of Huangjingzanyu group and better than those of large dosage,small dosage and wuziyangzong pill group.Sperm motility mode(LIN、STR、WOB、ALH、BCF、MAD)were not changed significantly in 3 different dosage of optimized formula. Conclusions :Huangjingzanyu optimized formula can increase sperm concentration,motility,viability and motility velocity.

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Key concepts: Motility, Sperm motility, Sperm, Tripterygium wilfordii, Andrology, Chemistry, Biology, Medicine