2014Lishizhen Medicine and Materia Medica ResearchRequires access

YiQiTongLuo Method in Treating Idiopathic Pulmonary Fibrosis: A Clinical Trial

LI Yan-ya

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Abstract

Objective To investigate the clinical effect and safety of yiqitongluo method(feibitongfang) on patients with idiopathic pulmonary fibrosis. Methods The 52 patients were randomly divided into the treatment and control groups. The treatment group is treated with Feibitongfang. The control group is treated with prednisone. The therapeutic course of both the groups was 12 weeks.Results Feibitongfang and prednisone can improve comprehensive curative effect,but the treatment group had not improved compared with the control group in it. Feibitongfang had bigger improvement in the symptoms of dyspnea,dry cough,chest complaint(P 0. 05). There was no significant difference for the patients of the control group in relieving languor and debilitation after treating. For pulmonary function after the treatment there was no effect improved in the treatment group compared with pretherapy(P 0. 05). The VC(%) significantly decreased in the control group after treating(P 0. 05). And for the changing of the DLCO(%)between the two groups there was significantly difference(P 0. 05),the effect of the control group was better than that of the treatment group. There was no adverse reactions in the treatment group. Conclusion Patients with IPF may benefit from the treatment with Feibitongfang,can delay the progression of disease and improve the quality of life.

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What this paper is about

Objective To investigate the clinical effect and safety of yiqitongluo method(feibitongfang) on patients with idiopathic pulmonary fibrosis. Methods The 52 patients were randomly divided into the treatment and control groups. The treatment group is treated with Feibitongfang. The control group is treated with prednisone. The therapeutic course of both the groups was 12 weeks.Results Feibitongfang and prednisone can improve comprehensive curative effect,but the treatment group had not improved compared with the control group in it. Feibitongfang had bigger improvement in the symptoms of dyspnea,dry cough,chest complaint(P 0. 05). There was no significant difference for the patients of the control group in relieving languor and debilitation after treating. For pulmonary function after the treatment there was no effect improved in the treatment group compared with pretherapy(P 0. 05). The VC(%) significantly decreased in the control group after treating(P 0. 05). And for the changing of the DLCO(%)between the two groups there was significantly difference(P 0. 05),the effect of the control group was better than that of the treatment group. There was no adverse reactions in the treatment group. Conclusion Patients with IPF may benefit from the treatment with Feibitongfang,can delay the progression of disease and improve the quality of life.

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Available abstract

Objective To investigate the clinical effect and safety of yiqitongluo method(feibitongfang) on patients with idiopathic pulmonary fibrosis. Methods The 52 patients were randomly divided into the treatment and control groups. The treatment group is treated with Feibitongfang. The control group is treated with prednisone. The therapeutic course of both the groups was 12 weeks.Results Feibitongfang and prednisone can improve comprehensive curative effect,but the treatment group had not improved compared with the control group in it. Feibitongfang had bigger improvement in the symptoms of dyspnea,dry cough,chest complaint(P 0. 05). There was no significant difference for the patients of the control group in relieving languor and debilitation after treating. For pulmonary function after the treatment there was no effect improved in the treatment group compared with pretherapy(P 0. 05). The VC(%) significantly decreased in the control group after treating(P 0. 05). And for the changing of the DLCO(%)between the two groups there was significantly difference(P 0. 05),the effect of the control group was better than that of the treatment group. There was no adverse reactions in the treatment group. Conclusion Patients with IPF may benefit from the treatment with Feibitongfang,can delay the progression of disease and improve the quality of life.

Key concepts: Medicine, DLCO, Pulmonary function testing, Prednisone, Treatment and control groups, Internal medicine, Pulmonary fibrosis, Therapeutic effect

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