ScholarLens Back to search
2006•Huazhong Nongye Daxue xuebaoRequires access

Post-antibiotic Effect of Florfenicol against Pasteurella multocida(birds) in vitro

Xu Zhang, Wang Da-ju, Jine Wu

Open publisher page 1 citations

Abstract

The post-antibiotic effect(PAE),the post-antibiotic sub-MIC effect(PA-SME) and sub-MIC effect(SME) of florfenicol(Ff) against Pasteurella multocida in vitro were determined in this study.Mueller-Hinton agar colony counting method was used to monitorthe growth of bacteria. The results showed that PAEs of Ff against P.multocidaat 2～8×MIC were 1.31～5.01 h,PA-SMEs(1.66)~24.2 h and SMEs 0.05~1.31 h.It was demonstrated that Ff against P.multocidawas affected by the concentration of antimicrobial agents,the exposure time and the concentration of organism.This study suggested that the administrationscheme of Ff againstP.multocid should be considered to combineits pharmacokinetic parameters,MIC and PAE.

About this research paper

What this paper is about

The post-antibiotic effect(PAE),the post-antibiotic sub-MIC effect(PA-SME) and sub-MIC effect(SME) of florfenicol(Ff) against Pasteurella multocida in vitro were determined in this study.Mueller-Hinton agar colony counting method was used to monitorthe growth of bacteria. The results showed that PAEs of Ff against P.multocidaat 2～8×MIC were 1.31～5.01 h,PA-SMEs(1.66)~24.2 h and SMEs 0.05~1.31 h.It was demonstrated that Ff against P.multocidawas affected by the concentration of antimicrobial agents,the exposure time and the concentration of organism.This study suggested that the administrationscheme of Ff againstP.multocid should be considered to combineits pharmacokinetic parameters,MIC and PAE.

Why it matters

OpenAlex reports 1 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

The post-antibiotic effect(PAE),the post-antibiotic sub-MIC effect(PA-SME) and sub-MIC effect(SME) of florfenicol(Ff) against Pasteurella multocida in vitro were determined in this study.Mueller-Hinton agar colony counting method was used to monitorthe growth of bacteria. The results showed that PAEs of Ff against P.multocidaat 2～8×MIC were 1.31～5.01 h,PA-SMEs(1.66)~24.2 h and SMEs 0.05~1.31 h.It was demonstrated that Ff against P.multocidawas affected by the concentration of antimicrobial agents,the exposure time and the concentration of organism.This study suggested that the administrationscheme of Ff againstP.multocid should be considered to combineits pharmacokinetic parameters,MIC and PAE.

Key concepts: Pasteurella multocida, Florfenicol, Antibiotics, Microbiology, Antimicrobial, Agar, Biology, In vitro

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Post-antibiotic Effect of Florfenicol against Pasteurella multocida(birds) in vitro — Research Paper | ScholarLens