Analysis of Sputum Culture of Bacteria in Patients with Lower Respiratory Tract Infection

Objective To investigate the distribution and drug resistance of bacterial isolates from sputum in elderly patients with lower respiratory tract infection,and to provide reasonable evidence for the clinical use of antibiotics to reduce the rate of bacterial resistance and the formation of multi-drug resistance.Methods Sputum specimens bacterial culture and sensitivity test positive results of all hospitalized patients with lower respiratory tract infections were collected during the period of 2009 to 2010.Results In 2009,Gram negative bacillus accounted for 53.3% of the sputum culture,the Gram-positive coccus 30%,and the fungus 16.7%.In 2010,Gram-negative bacillus accounted for 42.9%,followed by fungus(38.1%),the last for Gram-positive coccus(19.0%).In 2009 and 2010,the top three gram-negative bacillus were the same: Klebsiella pneumonia,Pseudomonas aeruginosa,and Escherichia coli.The Gram-positive coccus were as follows: Staphylococcus aureus,Streptococcusviridans and Enterococcus faecalis.Conclusion From 2009 to 2010,sputum culture of bacteria distribution took the Gram negative bacillus primarily,fungus infection risk in 2010 was higher than that in 2009.