2005•Journal of Hepatobiliary SurgeryRequires access

ANALYSIS ON RISK FACTORS LEADING INCOMPLETE COMPENSATION OF LIVER FUNCTION AFTER HEPATECTOMY FOR PRIMARY LIVER CANCER

Chen Shan-rong

Abstract

Objective To explore the risk factors affecting liver function after hepatectomy of primary liver cancer(PLC) and their preventions and treatments.Methods Clinical data of 92 cases with PLC receiving hepatectomy in recent six years were analyzed retrospectively.Result Lightly incomplete compensation of liver function(Child B) was found in 23 cases(25%),seriously incomplete compensation(Child C) in 6 cases(6.5%),and 3 cases(3.3%) died in one month after hepatectomy.The univariate analysis revealed: Tumor diameter(P0.01),operative procedure(P0.01),liver cirrhosis(P0.05) and blood loss(P0.05) were significantly related with incomplete compensation of liver function after hepatectomy of PLC.Conclusion The main risk factors leading incomplete compensation of liver function were tumor diameter 10 cm,regular hemi-hepatectomy,liver cirrhosis and blood loss 1500 ml.Controlling intraoperative blood loss and preserving more functioning liver tissue were the important measures to enhance safety for hepatectomy and to decrease the postoperative complications.

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Key concepts: Medicine, Hepatectomy, Cirrhosis, Liver function, Liver cancer, Blood loss, Univariate analysis, Surgery