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2013•China Medicine and PharmacyRequires access

Determination of Gemcitabine hydrochloride by potentiometric titration

Qiong Tang

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Abstract

Objective To establish the determination of assay for Gemcitabine hydrochloride. Methods The determination was carried out on potentiometric titration.The glacial acetic acid was solvent,titrate with 0.1 mol/L perchloric acid titration solution. Results There was obvious on titration process.The RSD for precision was 0.10%(n=6). Conclusion The Method was simple,accurate and rapid,which can be used for the determination of assay for gemcitabine hydrochloride.

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What this paper is about

Objective To establish the determination of assay for Gemcitabine hydrochloride. Methods The determination was carried out on potentiometric titration.The glacial acetic acid was solvent,titrate with 0.1 mol/L perchloric acid titration solution. Results There was obvious on titration process.The RSD for precision was 0.10%(n=6). Conclusion The Method was simple,accurate and rapid,which can be used for the determination of assay for gemcitabine hydrochloride.

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Available abstract

Objective To establish the determination of assay for Gemcitabine hydrochloride. Methods The determination was carried out on potentiometric titration.The glacial acetic acid was solvent,titrate with 0.1 mol/L perchloric acid titration solution. Results There was obvious on titration process.The RSD for precision was 0.10%(n=6). Conclusion The Method was simple,accurate and rapid,which can be used for the determination of assay for gemcitabine hydrochloride.

Key concepts: Medicine, Perchloric acid, Titration, Potentiometric titration, Chromatography, Acetic acid, Hydrochloride, Chemistry

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