Efficacy and safety of marvelon on the treatment of adolescent dysfunctional uterine bleeding

Objectives: To explore the clinic efficacy and safety of Desogestrel and Ethinylestradiol Tablets(marvelon) on adolescent dysfunctional uterine bleeding(ADUB).Method: Seventy-two ADUB patients were randomly divided into the experimental group(treated by marvelon) and the control group(treated by Premarin combined with medrysone).The control bleeding time and completely hemostatic time pre-and post-therapy of both the two groups were observed,and so were clinic efficacy and side effects.Results: The control bleeding time and completely hemostatic time of the experimental group were significantly shorter than those of the control group(P0.05).The total effective rate of the experimental group was significantly higher than that of the control group(χ2=4.18,P0.05).Five cases with side effects were found in the experimental group,three cases with nausea and two cases with discomfort in epigastrium.In the control group,fourteen cases with side effects were found,eleven cases with weight gain and three cases with nausea.The incidence rate of side effects of the experimental group was significantly lower than that of the control group(χ2=5.79,P0.05).Conclusion: Marvelon is safe and effective in treating patients with ADUB.Featuring quick hemostasis,it can be the drug of first choice for patients with ADUB.