The effect of exposure of Benzo(a)Pyrene,Pyrene and their mixture on hepatic glutathione-s-transferases activity in Mugil so-iuy
Wang Chong-gang
Abstract
Wang Chong-gang
Abstract
The effects of benzo(a)pyrene(BaP),pyrene and their mixture of equal concentration exposure on hepatic glutathione s-transferases(GST)activity in Mugil so-iuy were studied in experimental condition.The results showed that the GSTactivities were mostly induced in the fish exposed to BaP or pyrene during7days exposure.Pyrene seems to have a stronger ability inducing GSTactivity than BaP.No GSTactivity inducins were observed in the fish exposed to the mixture during a15day exposure,while the GST activity were inhibited at the anaphase of the exposure.These results suggested that the hepatic GSTactivity induction indicate PAHs pollution,while the GSTactivity inhibition indicate more grievous or long lasting pollution.
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The effects of benzo(a)pyrene(BaP),pyrene and their mixture of equal concentration exposure on hepatic glutathione s-transferases(GST)activity in Mugil so-iuy were studied in experimental condition.The results showed that the GSTactivities were mostly induced in the fish exposed to BaP or pyrene during7days exposure.Pyrene seems to have a stronger ability inducing GSTactivity than BaP.No GSTactivity inducins were observed in the fish exposed to the mixture during a15day exposure,while the GST activity were inhibited at the anaphase of the exposure.These results suggested that the hepatic GSTactivity induction indicate PAHs pollution,while the GSTactivity inhibition indicate more grievous or long lasting pollution.
Key concepts: Mugil, Pyrene, Chemistry, Benzo(a)pyrene, Glutathione, Fish <Actinopterygii>, Environmental chemistry, Biochemistry