2001•Unpublished venueRequires access

CHANGES AND SIGNIFICANCE OF CONCENTRATIONS OF LEUKEMIA INHIBITORY FACTOR OF OVUL ATORY FOLLICULAR FLUID IN IVF FEMALES

Wang Guo

Abstract

Objective:To detect the changes of concentrations of leukemia inhibitory factor of ovulatory follicular fluid in IVF females as well as to explore the relationship between LIF and follicular development and ovulation.Methods:Follicular fluid LIF and serum LIF concentrations in 45 IVF females were measured by sandwich enzymelinked immunoadsorbent assay(ELISA).Results:Follicular fluid concentrations of LIF〔(22.77±14.11)ng/L〕 were significantly higher than serum LIF concentrations 〔(3.20±1.25)ng/L〕 ( P0.001). Follicular fluid LIF concentrations of mature oocyte 〔(31.13±15.90)ng/L〕were significantly higher than follicular fluid LIF concentrations of premature oocyte 〔(11.91±9.13)ng/L〕( P0.001) .Conclusion:LIF may be a important cytokine in inducing follicular development and ovulation.

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Follicular fluid, Leukemia inhibitory factor, Ovulation, Oocyte, Follicular phase, Internal medicine, Endocrinology, Chemistry