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ChemInform Abstract: Enamine Chemistry. Part 29. Synthesis of Adamantane Derivatives from α,β‐Unsaturated Acid Chlorides and 4,4‐Disubstituted Cyclohexanone Enamines.

Peter W. Hickmott, Md. Giasuddin Ahmed, Salman Ahmed, Simon Wood, M. Kapon

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Abstract

Abstract The reaction of enamine (Ia) with (II) yields a mixture of diastereomers (IIIa)‐(Va), whose previously proposed structures can be confirmed by their reduction to (VII)‐(IX) and by an X‐ray analysis of (IVa) (space group P2,2,2" Z=4).

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Abstract The reaction of enamine (Ia) with (II) yields a mixture of diastereomers (IIIa)‐(Va), whose previously proposed structures can be confirmed by their reduction to (VII)‐(IX) and by an X‐ray analysis of (IVa) (space group P2,2,2" Z=4).

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Available abstract

Abstract The reaction of enamine (Ia) with (II) yields a mixture of diastereomers (IIIa)‐(Va), whose previously proposed structures can be confirmed by their reduction to (VII)‐(IX) and by an X‐ray analysis of (IVa) (space group P2,2,2" Z=4).

Key concepts: Enamine, Cyclohexanone, Chemistry, Diastereomer, Adamantane, Organic chemistry, Medicinal chemistry, Stereochemistry

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ChemInform Abstract: Enamine Chemistry. Part 29. Synthesis of Adamantane Derivatives from α,β‐Unsaturated Acid Chlorides and 4,4‐Disubstituted Cyclohexanone Enamines. — Research Paper | ScholarLens