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2003•Journal of Zhenjiang Medical CollegeRequires access

Effect of Different Concentrations of Mifepristone on Human Uterine Leiomyoma Cells in Vitro

Yang Yan

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Abstract

Objective:To observe the effect of mifepristone on the human uterine leiomyoma cells in vitro. Methods :Human uterine leiomyoma cells were treated with mifepristone at different concentrations and the growth of the cells was analyzed by plotting cell growth curve and MTT assay.Results:Lower concentration of mifepristone had no inhibitory effect on the human uterine leiomyoma cells, The effect developed when the concentration was up to 16 -6 mol/L,and the inhibitory effect of mifepristone became more significant with the increase of the concentration.Conclusions:The effect of mifepristone on human leiomyoma cells in vitro is concentration-dependent.

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What this paper is about

Objective:To observe the effect of mifepristone on the human uterine leiomyoma cells in vitro. Methods :Human uterine leiomyoma cells were treated with mifepristone at different concentrations and the growth of the cells was analyzed by plotting cell growth curve and MTT assay.Results:Lower concentration of mifepristone had no inhibitory effect on the human uterine leiomyoma cells, The effect developed when the concentration was up to 16 -6 mol/L,and the inhibitory effect of mifepristone became more significant with the increase of the concentration.Conclusions:The effect of mifepristone on human leiomyoma cells in vitro is concentration-dependent.

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Available abstract

Objective:To observe the effect of mifepristone on the human uterine leiomyoma cells in vitro. Methods :Human uterine leiomyoma cells were treated with mifepristone at different concentrations and the growth of the cells was analyzed by plotting cell growth curve and MTT assay.Results:Lower concentration of mifepristone had no inhibitory effect on the human uterine leiomyoma cells, The effect developed when the concentration was up to 16 -6 mol/L,and the inhibitory effect of mifepristone became more significant with the increase of the concentration.Conclusions:The effect of mifepristone on human leiomyoma cells in vitro is concentration-dependent.

Key concepts: Mifepristone, Leiomyoma, Uterine leiomyoma, In vitro, Andrology, Chemistry, Endocrinology, Internal medicine

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