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2011•China Medical HeraldRequires access

The clinical observation of the treatment on chronic hepatitis B by Interferon,Lamivudine and Adefovir dipivoxil

Zeng Shu

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Abstract

Objective:To explore the efficacy of the treatment on chronic hepatitis B by Interferon,Lamivudine and Ade-fovir dipivoxil.Methods:123 cases of chronic hepatitis B were randomly divided into three groups,Interferon group,Lamivudine group and Adefovir dipivoxil group,41 cases in each group,they were given the Interferon,Lamivudine and Adefovir dipivoxil respectively.Then compared the efficacy of the three groups.Results:The negative conversion rate of HBeAg in the Interferon group,Lamivudine group and Adefovir dipivoxil group was respectively 9.76%,29.27%,34.15%,the negative conversion rate of HBV-DNA was respectively 36.59%,60.98% and 56.09%,the normalization rate of ALT was respectively 41.46%,58.54% and 68.29%,there were significant differences between each two groups.Conclusion:Lamivudine and Adefovir dipivoxil are effective drug in the treatment of chronic hepatitis B.

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Objective:To explore the efficacy of the treatment on chronic hepatitis B by Interferon,Lamivudine and Ade-fovir dipivoxil.Methods:123 cases of chronic hepatitis B were randomly divided into three groups,Interferon group,Lamivudine group and Adefovir dipivoxil group,41 cases in each group,they were given the Interferon,Lamivudine and Adefovir dipivoxil respectively.Then compared the efficacy of the three groups.Results:The negative conversion rate of HBeAg in the Interferon group,Lamivudine group and Adefovir dipivoxil group was respectively 9.76%,29.27%,34.15%,the negative conversion rate of HBV-DNA was respectively 36.59%,60.98% and 56.09%,the normalization rate of ALT was respectively 41.46%,58.54% and 68.29%,there were significant differences between each two groups.Conclusion:Lamivudine and Adefovir dipivoxil are effective drug in the treatment of chronic hepatitis B.

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Available abstract

Objective:To explore the efficacy of the treatment on chronic hepatitis B by Interferon,Lamivudine and Ade-fovir dipivoxil.Methods:123 cases of chronic hepatitis B were randomly divided into three groups,Interferon group,Lamivudine group and Adefovir dipivoxil group,41 cases in each group,they were given the Interferon,Lamivudine and Adefovir dipivoxil respectively.Then compared the efficacy of the three groups.Results:The negative conversion rate of HBeAg in the Interferon group,Lamivudine group and Adefovir dipivoxil group was respectively 9.76%,29.27%,34.15%,the negative conversion rate of HBV-DNA was respectively 36.59%,60.98% and 56.09%,the normalization rate of ALT was respectively 41.46%,58.54% and 68.29%,there were significant differences between each two groups.Conclusion:Lamivudine and Adefovir dipivoxil are effective drug in the treatment of chronic hepatitis B.

Key concepts: Adefovir, Lamivudine, Medicine, Chronic hepatitis, Gastroenterology, Interferon, HBeAg, Internal medicine

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