2007•Journal of North China Coal Medical CollegeRequires access

Clinical analysis of nitric oxide,nitric oxide synthase and electroencephalograph in infants with febrile convulsion

Wang Kai-xia

Abstract

Objective To investigate the levels of nitric oxide(NO) and nitric oxide synthase(NOS) of cerebrospinal fluid and serum in infants with febrile convulsion,and study the relation between febrile convulsion mechanism and brain injury.Methods The levels of NO and NOS in cerebrospinal fluid and serum were measured by nitric acid reduction enzyme method and enzyme measured method respectively.Results NO levels and NOS activity of cerebrospinal fluid in febrile convulsion group were singnificantly lower than those in control group(P0.05).Conclusion The level of NO in cerebrospinal fluid and serum was singnificantly lower than that in control group.No may participate in anti-convulsion mechanism and play a role in anti-convulsion.

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Key concepts: Convulsion, Nitric oxide, Cerebrospinal fluid, Nitric oxide synthase, Medicine, Anesthesia, Febrile convulsions, Internal medicine