2009•PubMedRequires access

[Studies on flavones from Flos Chrysanthemi Indici].

Yi Tang, Meihua Gao, Meicun Yao

Abstract

OBJECTIVE: To study the chemical constituents of Flos Chrysanthemi Indici. METHODS: Chemical constituents were isolated and purified by silica gel and Sephadex LH-20 column chromatography. Their structures were indentified by means of physicochemical and spectral data. RESULTS: From the 80% ethanol extract of the material, seven compounds were isolated. Their structures were identified as luteolin (1), luteolin-7-O-beta-D-glucopyranoside (2), luteolin-7-O-(6"-O-acetyl)-beta-D-glucopyranoside (3), diosmetin (4), diosmetin-7-O-beta-D-glucopyranoside (5), eupatilin (6) and apigenin (7), respectively. CONCLUSION: Compounds 3-6 are isolated from Flos Chrysanthemi Indici for the first time.

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Key concepts: Flavones, Luteolin, Flos, Apigenin, Chemistry, Sephadex, Chromatography, Column chromatography