Acute Cerebral Infarction,Intravenous Thrombolysis or Selective Arterial Thrombolysis?

Objective Comparison of selective intra-arterial thrombolysis and intravenous thrombolysis efficacy and safety,to select an optimal way of treatment of acute cerebral infarction,reduce disability,improve patient quality of life,reduce the burden on families and society.Methods 60 patients were our department from November 2006 to September 2009 of the hospitalized patients were randomly divided into two groups,of which 32 patients with intravenous thrombolysis,intra-arterial thrombolysis in 28 cases.(1)intravenous thrombolysis:Intravenous infusion of urokinase;(2)Intra-arterial thrombolysis:From the femoral artery to the vascular occlusion site,local injection of urokinase.Respectively,before thrombolysis,after thrombolysis2 hours,1 day,3 days,7 days,14 days,28 days recording the U.S.National Institutes of Health neurological deficit score(NIHSS).Results Intra-arterial thrombolysis group was 78.6%,significantly effective rate 57.1%;intravenous thrombolysis group was 71.9%,significantly effective rate 31.3%;selective intra-arterial thrombolysis had significantly more efficient than intravenous thrombolysis group(P0.05).The total effective rate,cerebral hemorrhage,no significant difference in mortality.Conclusion Interventional thrombolysis compared with intravenous thrombolysis,intra-arterial thrombolysis interventional neurological deficit left behind by less,even more significant effect.It should be in a hospital surgical conditions,actively promoted.