2012China Medical HeraldRequires access

The value analysis of cardiac troponin I levels detection in patients with chronic heart failure

Wei Xiang

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Abstract

Objective To investigate clinical value of cardiac troponin I(cTnI) levels in patients with chronic heart failure.Methods CTnI levels of 114 patients with chronic heart failure were checked.The correlation among cTnI and cardiac function,left ventricular ejection fraction and cardiac structure were analyzed.Results The cardiac function class Ⅳ in patients with CHF cTnI levels were significantly higher than class Ⅲ and class Ⅱ patients(t = 13.23,9.62,P 0.01),class Ⅲ patients′ cTnI level were significantly higher than that of class Ⅱ patients(t = 7.54,P 0.01),and LVEF40% patients′ cTnI levels were significantly higher than that of LVEF 40%-50%,LVEF50% patients(t=18.34,13.86,P 0.01).LAD and LVEDd in CTnI elevated group were significantly higher than those of the normal group(t = 6.54,7.45,P 0.01),and LVS,LVPW in normal group was significantly higher than elevated group,the difference was statistically significant(t = 16.54,8.78,P 0.01).Conclusion cTnI level can reflect cardiac function in patients with CHF,left ventricular ejection conditions and ventricular remodeling situation.It's worthy of promotion and application.

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Objective To investigate clinical value of cardiac troponin I(cTnI) levels in patients with chronic heart failure.Methods CTnI levels of 114 patients with chronic heart failure were checked.The correlation among cTnI and cardiac function,left ventricular ejection fraction and cardiac structure were analyzed.Results The cardiac function class Ⅳ in patients with CHF cTnI levels were significantly higher than class Ⅲ and class Ⅱ patients(t = 13.23,9.62,P 0.01),class Ⅲ patients′ cTnI level were significantly higher than that of class Ⅱ patients(t = 7.54,P 0.01),and LVEF40% patients′ cTnI levels were significantly higher than that of LVEF 40%-50%,LVEF50% patients(t=18.34,13.86,P 0.01).LAD and LVEDd in CTnI elevated group were significantly higher than those of the normal group(t = 6.54,7.45,P 0.01),and LVS,LVPW in normal group was significantly higher than elevated group,the difference was statistically significant(t = 16.54,8.78,P 0.01).Conclusion cTnI level can reflect cardiac function in patients with CHF,left ventricular ejection conditions and ventricular remodeling situation.It's worthy of promotion and application.

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Available abstract

Objective To investigate clinical value of cardiac troponin I(cTnI) levels in patients with chronic heart failure.Methods CTnI levels of 114 patients with chronic heart failure were checked.The correlation among cTnI and cardiac function,left ventricular ejection fraction and cardiac structure were analyzed.Results The cardiac function class Ⅳ in patients with CHF cTnI levels were significantly higher than class Ⅲ and class Ⅱ patients(t = 13.23,9.62,P 0.01),class Ⅲ patients′ cTnI level were significantly higher than that of class Ⅱ patients(t = 7.54,P 0.01),and LVEF40% patients′ cTnI levels were significantly higher than that of LVEF 40%-50%,LVEF50% patients(t=18.34,13.86,P 0.01).LAD and LVEDd in CTnI elevated group were significantly higher than those of the normal group(t = 6.54,7.45,P 0.01),and LVS,LVPW in normal group was significantly higher than elevated group,the difference was statistically significant(t = 16.54,8.78,P 0.01).Conclusion cTnI level can reflect cardiac function in patients with CHF,left ventricular ejection conditions and ventricular remodeling situation.It's worthy of promotion and application.

Key concepts: Medicine, Ejection fraction, Troponin I, Internal medicine, Cardiology, Heart failure, Cardiac function curve, Myocardial infarction

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