Study Progress of Fiber-Based Tissue-Engineered Heart Valve Scaffold

The disease caused by heart valve damage or defect has become one of the major diseases which have threaten human health.The tissue-engineered scaffold prepared by fiber technology has good mechanical and biological properties,thus this technology gradually becomes the main method.This paper focused on the research progress of fiber-based tissue-engineered heart valve scaffold and compared the characteristics among different micro and nano fiber-based scaffolds molding by knitting,non-woven and electrospinning.In the future,three-dimensional porous nanofiber-based scaffold with excellent biocompatibility and controllable mechanical property will be the development direction of the tissueengineered heart valve scaffold.