In 171 couples with spontaneous abortion chromosome karyotype analysis

Objective: To study the relationship between spontaneous abortion and abnormal chromosome karyotype.Methods: A total of 171 couples with spontaneous abortions in the peripheral slices karyotype chromosome abnormal status statistics.Results: In 171 couples with spontaneous abortion,abnormal chromosome karyotype in 20 cases,abnormal chromosome karyotype detection rate was 5.87%(20 / 342),In 20 patients with abnormal karyotype of chromosome translocation in 4 robersonian translocation(20%) robertson;3 cases of reciprocal translocation(15%);Chromosomal inversions in 7 cases(35%);mosaic in 1 cases(5%);Chromosome polymorphism in 5 cases(25%).With the increase of times of spontaneous abortion,karyotypic abnormalities in the proportion of the increase,the proportion had statistical significance.Conclusion: spontaneous abortion pregnant women and couples with chromosomal abnormalities are closely related.