2009Yaowu fenxi zazhiRequires access

Study on extraction and determination of magnolol and honokiol in Baoji pills

Ning Jiang

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Abstract

Objective:To establish and improve a method for the quickly extraction and determination of magnolol and honokiol in Baoji pills.Methods:Magnolol and honokiol were quickly extracted on ASE300 system.Magnolol and honokiol were separated on DiamonsilTMC18 column(250 mm×4.6 mm,5 μm)and detected at 294 nm,using methanol-water-acetic acid glacial(79∶21∶0.25)as mobile phase,flow rate at 1.0 mL·min-1.Results:The standard curves for magnolol and honokiol were linear in the range of 6.25-400 μg·mL-1.The average recoveries(n=6)of magnolol and honokiol were 99.50% and 99.91%.Conclusions:The method is simple,rapid and accurate.

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What this paper is about

Objective:To establish and improve a method for the quickly extraction and determination of magnolol and honokiol in Baoji pills.Methods:Magnolol and honokiol were quickly extracted on ASE300 system.Magnolol and honokiol were separated on DiamonsilTMC18 column(250 mm×4.6 mm,5 μm)and detected at 294 nm,using methanol-water-acetic acid glacial(79∶21∶0.25)as mobile phase,flow rate at 1.0 mL·min-1.Results:The standard curves for magnolol and honokiol were linear in the range of 6.25-400 μg·mL-1.The average recoveries(n=6)of magnolol and honokiol were 99.50% and 99.91%.Conclusions:The method is simple,rapid and accurate.

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Available abstract

Objective:To establish and improve a method for the quickly extraction and determination of magnolol and honokiol in Baoji pills.Methods:Magnolol and honokiol were quickly extracted on ASE300 system.Magnolol and honokiol were separated on DiamonsilTMC18 column(250 mm×4.6 mm,5 μm)and detected at 294 nm,using methanol-water-acetic acid glacial(79∶21∶0.25)as mobile phase,flow rate at 1.0 mL·min-1.Results:The standard curves for magnolol and honokiol were linear in the range of 6.25-400 μg·mL-1.The average recoveries(n=6)of magnolol and honokiol were 99.50% and 99.91%.Conclusions:The method is simple,rapid and accurate.

Key concepts: Honokiol, Magnolol, Chemistry, Chromatography, Extraction (chemistry)

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