Effects of Perilla frutescens britt-Evening primrose Extractive on Lipid Metabolism and Immune Function in Broilers

Six hundred one-day-old Avian broilers were divided into five groups.Each group had six repeats of twenty birds.Group 1 was fed a basal diet,Group 2 was fed a basal diet supplemented with 50 mg·kg-1 aureomycin.Group 3,4,5 were fed a basal diet supplemented with 250,375,500 mg·kg-1 perilla frutescens britt-evening primrose extractive respectively.The effects of perilla frutescens britt-evening primrose extractive on lipid metabolism and immune function were studied.The results indicated that the contents of serum TG and TC of all experiment groups(group3,4,5) were lower than that in control group,especially 375 mg·kg-1 additive group was the lowest(p﹤0.05),the contents of serum TG and TC in it was decreased by 5.39% and 2.64% than blank control group;and there was a tendency to decrease the content of LDL-C in experiment groups(p﹥0.05).At the age of 3 weeks,the index of immune organ was promoted by the perilla frutescens britt-evening primrose extractive,especially index of the thymus and bursa of fabricius in 375 mg·kg-1 additive group were higher by 21.99% and 17.98% individually compared with blank control group significantly(p﹤0.05),however it had no great effects at 6 week old.at the age of 3 weeks,Lymphocyte ANAE+ rate of experiment1 and experiment 2 was 43.73% and 44.68% respectively,higher than control group(p﹤0.05).and content of the Newcastle Disease(ND) hemagglutination inhibition(HI) antibody titer in blood in experiment1 and experiment 2 was increased(p﹤0.05),however it had no dosage effect.It was concluded that added perilla frutescens britt-evening primrose extractive could enhance immune function and decrease lipid of broiler than that not added group significantly,in which 375 mg·kg-1 dosage was the best in the three experiment groups.