Clinical Effects of triamcinolone acetonide for serious macular edema diabetic

Objective To evaluate the therapeutic effect of intravitreal injection of triamcinolone acetonide(TA)in the treatment for serious diabetic macular edema.Methods A total of 36 patients(42 eyes)diagnosed with serious macular edema diabetic.These patients underwent intravitreous injection of triamcinolone acetonide(import)(4 mg/0.1 ml).Observation of before and after treatment four indicators:best corrected visual acuity,intraocular pressure(IOP),fundus fluorescence angiography(FFA) and optic coherence tomography(OCT).The follow-up period ranged from 6 months to 12 months average 9 months.Results The 36 patients(42 eyes) age of patients ranged from 45 to 70(mean 57)years.Before treatment FFA showed leakage significantly,after treatment significantly reduced leakage.The macular foveal thickness was(579.5±65)μm on average measured by 0 cT before the treatment and decreased to a mean of(265±78)μm at 6 months after injection of TA(P0.05).The mean postoperative bestcorrected visual acuity was0.01~0.2,average 0.1,after treatment for0.2~0.4,average 0.3(P0.05).The IOP of all patients were increased,and the scope of IOP elevation was from 8 to 20.0(mean 14)mm Hg.7 cases(7 eyes)beyong the normal intraocular pressure range,after treatment IOP were control,no serious complications occurred.Conclusion Intravitreal triamcinolone acetonide injection seems to be a promising treatment option for serious diabetic macular edema,visuaI acuity of patients with mild improvement,after treatment FFA showed,the macular area of fluorescein leakage significantly reduced,OCT examination confirmed the macular thickness decreases.