Monitoring of Serum Antibody after Measles Immunization on Children in Yuxi City
Wei Wang
Abstract
Wei Wang
Abstract
[Objective]To understand the measles antibody levels of children under 15 years after immunization in Yuxi City,and provide scientific evidence for measles elimination.[Methods]Stratified cluster sampling method was adopted to select 3 counties(Hongta District,Jiangchuan County,Yuanjiang County) from Yuxi City,350 from each county were sampled for immunization investigation according to PPS sampling method.The qualified serum samples were collected for measles IgG antibody test.[Results]Of1043 surveyed children,the positive rate of measles antibody was 94.92%,GMT was 1:1080.93.The positive rates of the 3 counties were all over 94.68%,while GMT ranged from 936.10 to 1321.56;the difference of measles antibody positive rate was not significant between counties,but significant between age groups(χ2 = 14.20,P 0.01),the positive rate was relatively low in basic immunization group of 1 year old(91.91%) ;the measles antibody positive rate was not significantly different between genders,but significantly different between children with different census registration(χ2 = 13.52,P 0.05).[Conclusion]Protective antibody IgG has generated effectively in children's body after measles immunization in Yuxi City.Immune barrier has formed solidly among children aged 1 ~ 15 years,which plays an important role in measles control.
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[Objective]To understand the measles antibody levels of children under 15 years after immunization in Yuxi City,and provide scientific evidence for measles elimination.[Methods]Stratified cluster sampling method was adopted to select 3 counties(Hongta District,Jiangchuan County,Yuanjiang County) from Yuxi City,350 from each county were sampled for immunization investigation according to PPS sampling method.The qualified serum samples were collected for measles IgG antibody test.[Results]Of1043 surveyed children,the positive rate of measles antibody was 94.92%,GMT was 1:1080.93.The positive rates of the 3 counties were all over 94.68%,while GMT ranged from 936.10 to 1321.56;the difference of measles antibody positive rate was not significant between counties,but significant between age groups(χ2 = 14.20,P 0.01),the positive rate was relatively low in basic immunization group of 1 year old(91.91%) ;the measles antibody positive rate was not significantly different between genders,but significantly different between children with different census registration(χ2 = 13.52,P 0.05).[Conclusion]Protective antibody IgG has generated effectively in children's body after measles immunization in Yuxi City.Immune barrier has formed solidly among children aged 1 ~ 15 years,which plays an important role in measles control.
Key concepts: Measles, Immunization, Medicine, Antibody, Immunology, Cluster sampling, Pediatrics, Vaccination