The clinical significance of serum PCT level,CRP and WBC in infants with severe Pneumonia caused by different morbigenous pathogens

Objective Investigate the differences and the clinical significance of serum PCT level,CRP level and WBC count in infants with severe Pneumonia caused by Different morbigenous pathogens.Methods eighty-six children diagnosed as pneumonia patients from 2007.1 to 2007.8 in our hospital were enrolled.The venous blood samples were obtained at acute period and recovery stage.Use immunoluminometric assay to measure the PCT level and use immunoturbidimetry to measure the CRP level.Results The PCT level of patients with sever Pneumonia at acute stage is higher than normal children,0.5 ng/mL,and it has slight increase in patients with Viral Pneumonia and Mycoplasmal Pneumonia,0.5 ng/mL;Compared with Mycoplasmal Pneumonia,the PCT levels have some significant differences between children with Bacterial Pneumonia and Viral Pneumonia(P0.01),but no significant difference between the Viral one and the Mycoplasmal one(P0.05);The CPR level has marketable difference in Bacterial Pneumonia when contrasted to Viral Pneumonia and Mycoplasmal Pneumonia and no marketable difference between them(P0.05).The WBC count of Viral Pneumonia has significant difference compared with that of Bacterial Pneumonia(P0.01),but when it compared with it in Mycoplasmal Pneumonia,there is no significant difference.Conclusion In clinical examination,it will be helpful to diagnosis the Bacterial Pneumonia at early stage and it can also direct the therapy according to the serum PCT and CRP,WBC and the form of the cell.But,the detecting of PCT cannot substitute the examination of Mycoplasmal antibody,and comprehensive judgment of the Mycoplasmal infect or the viral infect is considered with the characteristics of age,clinical symptom,signs of lungs,chest film and examination of aetiology etc.