2014Guiding Journal of Traditional Chinese Medicine and PharmacyRequires access

The Clinical Research of the TCM Syndromes Distribution of Small Cell Lung Cancer

Qian Dong

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Abstract

Objective: To explore the TCM syndromes distribution of small cell lung cancer. Methods: There were 100 cases of patients with SCLC selected, to investigate the TCM syndrome distribution and analysis the impact of TNM stage and the chemotherapy on the TCM syndrome distribution. Results: The main TCM syndrome type of the SCLC were 8 cases of qi deficiency syndrome(8.0%), 20 cases of qi and Yin deficiency syndrome(20.0%), 11 cases of Yin deficiency and phlegm heat(11.0%), 26 cases of qi deficiency and phlegm dampness syndromes(26.0%), and 35 cases of qi stagnation and blood stasis syndrome(35.0%). Qi deficiency syndrome is more common in the TNM staging of patients with stage I disease, and qi stagnation and blood stasis syndrome is more common in stage IV patients, with statistically significant difference(P0.05). After 4 cycles of chemotherapy, The constituent ratio of qi and Yin deficiency syndrome and qi deficiency and phlegm dampness syndromes rose; and the constituent ratio ofYin deficiency and phlegm heat syndromes, the constitute of qi stagnation and blood stasis syndrome decreased, with statistically significant difference(P0.05). Conclusion: The main TCM syndromes of SCLC is intermingled deficiency and excess, which is associated with TNM staging; the main syndromes before chemotherapy was qi stagnation and blood stasis syndrome; the main syndromes are qi and Yin deficiency syndrome and qi deficiency and phlegm dampnes syndrome after chemotherapy; this can provide theoretical basis for the intervention of traditional Chinese medicine for the SCLC.

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Objective: To explore the TCM syndromes distribution of small cell lung cancer. Methods: There were 100 cases of patients with SCLC selected, to investigate the TCM syndrome distribution and analysis the impact of TNM stage and the chemotherapy on the TCM syndrome distribution. Results: The main TCM syndrome type of the SCLC were 8 cases of qi deficiency syndrome(8.0%), 20 cases of qi and Yin deficiency syndrome(20.0%), 11 cases of Yin deficiency and phlegm heat(11.0%), 26 cases of qi deficiency and phlegm dampness syndromes(26.0%), and 35 cases of qi stagnation and blood stasis syndrome(35.0%). Qi deficiency syndrome is more common in the TNM staging of patients with stage I disease, and qi stagnation and blood stasis syndrome is more common in stage IV patients, with statistically significant difference(P0.05). After 4 cycles of chemotherapy, The constituent ratio of qi and Yin deficiency syndrome and qi deficiency and phlegm dampness syndromes rose; and the constituent ratio ofYin deficiency and phlegm heat syndromes, the constitute of qi stagnation and blood stasis syndrome decreased, with statistically significant difference(P0.05). Conclusion: The main TCM syndromes of SCLC is intermingled deficiency and excess, which is associated with TNM staging; the main syndromes before chemotherapy was qi stagnation and blood stasis syndrome; the main syndromes are qi and Yin deficiency syndrome and qi deficiency and phlegm dampnes syndrome after chemotherapy; this can provide theoretical basis for the intervention of traditional Chinese medicine for the SCLC.

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Available abstract

Objective: To explore the TCM syndromes distribution of small cell lung cancer. Methods: There were 100 cases of patients with SCLC selected, to investigate the TCM syndrome distribution and analysis the impact of TNM stage and the chemotherapy on the TCM syndrome distribution. Results: The main TCM syndrome type of the SCLC were 8 cases of qi deficiency syndrome(8.0%), 20 cases of qi and Yin deficiency syndrome(20.0%), 11 cases of Yin deficiency and phlegm heat(11.0%), 26 cases of qi deficiency and phlegm dampness syndromes(26.0%), and 35 cases of qi stagnation and blood stasis syndrome(35.0%). Qi deficiency syndrome is more common in the TNM staging of patients with stage I disease, and qi stagnation and blood stasis syndrome is more common in stage IV patients, with statistically significant difference(P0.05). After 4 cycles of chemotherapy, The constituent ratio of qi and Yin deficiency syndrome and qi deficiency and phlegm dampness syndromes rose; and the constituent ratio ofYin deficiency and phlegm heat syndromes, the constitute of qi stagnation and blood stasis syndrome decreased, with statistically significant difference(P0.05). Conclusion: The main TCM syndromes of SCLC is intermingled deficiency and excess, which is associated with TNM staging; the main syndromes before chemotherapy was qi stagnation and blood stasis syndrome; the main syndromes are qi and Yin deficiency syndrome and qi deficiency and phlegm dampnes syndrome after chemotherapy; this can provide theoretical basis for the intervention of traditional Chinese medicine for the SCLC.

Key concepts: Blood stasis, Medicine, Phlegm, Traditional Chinese medicine, Internal medicine, Stage (stratigraphy), Yin deficiency, Disease

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