Evalution of LV Global and Regional Function in Patients with Heart Failure Due to Anterior Wall Myocardial Infarction Using Radionuclide Ventriculagraphy

Purpose:To assess left ventricular(LV) global and regional function of systolic and diastolic in the patients with anterior wall myocardial infarction,we analyzed high-temporal-resolution LV global and regional time-activity curves obtained from gated radionuclide ventriculargraphy.Methods:The patients were divided into three groups,one control group(G0) with 15 normal peoples,and two groups with patients with previous anterior wall myocardial infarction but without aneurysm,which included a first group(G1) with 25 patients in NYHA class 0,a second group(G2) with 24 patients in NYHA class Ⅱ or Ⅲ.The parameters included:(1) LV global systolic and diastolic function parameters,(2) LV regional systolic and diastolic function parameters.Results:(1) LV global systolic function: the parameters of LVEF,PER,1/3EF,1/3ER in G2 were reduced significantly than that in G0 and G1(P0.01).(2) LV global diastolic function: the parameters of PFR 1/3FF 1/3FR in G2 were reduced significantly than that in G0 and G1(P0.01).(3) LV regional systolic function: the parameter of LVREF in G2 were reduced significantly in all 6 LV regional segments than that in G0 and G1(P0.01).(4) LV regional distolic function: the parameter of LVR1/3FF in G2 were reduced significantly in all 6 LV regional segments than that in G0 and G1(P0.01).Conclusion: The development of left ventricular dysfunction and heart failure after anterior wall myocardial infarction had produced damage on left ventricular global and regional function of systolic and diastolic.