Rapid Determination of Cephradine in Capsules by Fluorescence Spectrometry
Yang Mei
Abstract
Yang Mei
Abstract
This paper studied the fluorescence spectra of cephradine in aqueous medium at pH 6~7 and developed a rapid method for the determination of cephradine.The fluorescence intensity is linearly related to the cephradine concentration in the range of 1.4 mg/L~1.4 g/L,the detection limit is 0.18 mg/L,the relative standard deviation is 1.3% for 1.4 mg/L cephradine( n =11).This method is simple ,rapid and can be used for the determination of cephradine in capsules with satisfactory results.
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This paper studied the fluorescence spectra of cephradine in aqueous medium at pH 6~7 and developed a rapid method for the determination of cephradine.The fluorescence intensity is linearly related to the cephradine concentration in the range of 1.4 mg/L~1.4 g/L,the detection limit is 0.18 mg/L,the relative standard deviation is 1.3% for 1.4 mg/L cephradine( n =11).This method is simple ,rapid and can be used for the determination of cephradine in capsules with satisfactory results.
Key concepts: Cephradine, Chemistry, Detection limit, Fluorescence, Relative standard deviation, Chromatography, Fluorescence spectrometry, Analytical Chemistry (journal)